BioImmersion -- Therapeutic Food Supplements

Welcome Friends,

We invite you to contribute articles & research, thoughts & poems, analysis & solutions; to publish and converse with old and new friends, fellow world citizens, dedicated to bring peace into the chaos of the globe we call home. We have seeded the blog with some articles and thoughts to get the conversation going. The categories on the right will expand as our entries and foci evolve. Lets start writing and publishing!

Contact us about publishing to the blog: publish@bioimmersion.com.

  • Fatty Liver

    Dear Friends

    Nonalcoholic fatty liver disease (NAFLD), defined by excessive lipid accumulation in the liver, is the hepatic manifestation of insulin resistance and the metabolic syndrome. Due to the epidemics of obesity, NAFLD is rapidly becoming the leading cause of altered liver enzymes in Western countries (Blachier et al., 2004).   A fatty liver may lead to a fatty pancreas which leads to diabetes (Lichtenstein, Schwab., 2000).

    Valenti et al. (2013) explain how steatosis (fatty liver) may be associated with oxidative hepatocellular damage, inflammation, and activation of fibrogenesis, defining nonalcoholic steatohepatitis (NASH).  And, NASH is potentially a progressive liver disease leading to cirrhosis and hepatocellular carcinoma.

    Therapeutic Foods support for Nonalcoholic Fatty Liver Disease:
    Fatty Liver Protocol 3

    • Blueberry Extract- one daily
    • Phyto Power- two daily
    • Cruciferous Sprouts Complex- two daily
    • Original Synbiotic- one tsp. daily

     

    Food Science:

    Anthocyanins decrease hepatic lipid accumulation and counteract oxidative stress and hepatic inflammation (Valenti, 2013; Zhu  et al., 2012; Guo et al., 2011).

    Blueberry Extract contains pure anthocyanin extract from Vaccinium corymbosum- a North American blueberry cultivar with an exception broad spectrum of anthocyanins.  It takes us 80 pounds of blueberries to get one pound of this precious extract.

    Phyto Power contains four species of wild-crafted Alaskan blueberries (the whole berry), with an exceptionally high concentration of anthocyanins. Plus, it contains the flavonoids of three species of whole wild-crafted rose hips (including seeds) and four species of wild-crafted Alaskan dandelion (including roots, leaves and flowers).  The roots increase liver bile flow.

    Dietary supplementation with broccoli sprout extract containing sulforaphane precursor glucoraphanin is likely to be highly effective in improving liver function through reduction of oxidative stress (Kikuchi, 2015).

    Cruciferous Sprouts Complex contains broccoli sprouts, daikon radish sprouts, red radish sprouts, water cress sprouts, kale sprouts, mustard sprouts and cabbage sprouts; all together containing high levels of not only glucosinolates, but also high levels of myrosinase (from red radish), the enzymes necessary for high production of sulforaphanes.

    The effects of probiotics and prebiotics have proven to be beneficial in NAFLD (Iacono, 2010; Yadav, 2007).

    The Original Synbiotic contains 5 pedigreed strains of L. acidophilus, L. rhamnosus, L. plantarum, S. thermophilus and B. longum, plus inulin derived from organic chicory root.

    Inulin is very bifidogenic, enhancing the growth of Lactobacillus as well.  These good bacterial produce copious amounts of butyrate upon the fermentation of inulin which facilitate the tightening of gut epithelial cell junctions—reducing leaky gut syndrome.  Delzenne and Kok (1999) demonstrated that FOS, modifying the gene expression of lipogenic enzymes, reduced the de novo liver fatty acid synthesis.

    Lactobacillus acidophilus reduced liver oxidative stress and improved insulin resistance (Yadav et al., 2007).  Lactobacillus plantarum reduced liver  and serum cholesterol and triglycerides (Wang et al., 2009).  Lactobacillus rhamnosus reduced hepatic steatosis (Lee 2006).

    Bibliography:

    • Blachier et al. (2004). The burden of liver disease in Europe: a review of available epidemiological data. Journal of Hepatology; 58(3): 593-608.
    • Browning et al. (2004). Prevalence of hepatic steatosis in an urban population in the United States: impact of ethnicity. Hepatology; 40(6): 1387-1395.
    • Delzenne NM, Kok NN. (1999). Biochemical basis of oligofructose3-induced hypolipidemia in animal models. J Nutr; 129: 1467S-1470S.
    • Guo et al. (2011). Anthocyanin inhibits high glucose-induced hepatic mtGRAT1 activation and prevents fatty acid synthesis through PKC. Journal of Lipid Research;52(5): 908-922.
    • Iacono et al. (2010). Probiotics as an emerging therapeutic strategy to treat NAFLD: focus on molecular and biochemical mechanisms. JNB; 22(8): 699-711.
    • Johnson-Henry et al. (2008). Lactobacillus rhamnosus strain GG prevents enterohemorrhagic Escherichia coli 0157:H7- Induced changes in epithelial barrier function. Infect Immun; 76:1340-1348.
    • Kikuchi et al. (2015). Sulforaphane-rich broccoli sprout extract improves hepatic abnormalities in male subjects. World J Gastroenterol; 21(43): 12457-12467.
    • Lee et al. (2006). Human originated bacteria, Lactobacillus rhamnosus PL60, produce conjugated linoleic acid and show anti-obesity effects in diet-induced obese mice. Biochim Biophys Acta; 1761: 736-744.
    • Lichtenstein AH, Schwab US. (2000). Relationship of dietary fat to glucose metabolism. Atherosclerosis; 150(2): 227-243.
    • Valenti et al. (2013). Dietary Anthocyanins as Nutritional Therapy for Non alcoholic Fatty Liver Disease. Oxidative Medicine and Cellular Longevity; Volume 2013:Article ID 145421.
    • Vendrame et al. (2013a). Wild Blueberry (Vaccinium angustifolium)-enriched diet improves dyslipidaemia and modulates the expression of genes related to lipid metabolism in obese Zucker rats. British Journal of Nutrition; 111(2): 194-200.
    • Wang et al. (2009). Effects of Lactobacillus plantarum MA2 isolated from Tibet kefir on lipid metabolism and intestinal microflora of rats fed on high-cholesterol diet. Appl Microbiol Biotechnol; 84: 341-347.
    • Yadav et al. (2007). Antidiabetic effect of probiotic dahl containing Lactobacillus acidophilus and Lactobacillus casei in high fructose fed rats. Nutrition; 23: 62-68.
    • Zhu et al. (2012). The anthocyanin cyaniding-3-O-beta-glucoside, a flavonoid, increases hepatic glutathione synthesis and protects hepatocytes against reactive oxygen species during hyperglycemia: involvement of a cAMP-PKA-dependent signaling pathway. Free Radical Biology and Medicine; 52(2): 314-327.

    Yours,

    Seann Bardell

    We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please  use our products under the advisement of your doctor.

     

    Green Facts:

    Globe_Home 3

    Michael Gregor in his educational series shows how saturated fat in the diet causes insulin resistance which leads to fatty muscles leading to fatty liver leading to fatty pancreas leading to diabetes: What Causes Insulin Resistance? and Diabetes as a Disease of Fat Toxicity.
  • Metabolic Syndrome

    Dear Friends

    Metabolic Syndrome is a disorder that now affects about 1/4 of the American population and has emerged as a worldwide epidemic.  It may soon replace smoking as the leading cause for Coronary Heart Disease—the number one cause of death for men and women in the US (NIH: NHLBI, 2015). Additionaly, Metabolic Syndrome is causative for diabetes, NAFLD and cancer.

    The risk factors for Metabolic Syndrome are (Grundy 2004, McCullough 2011):

    • Abdominal obesity
    • Atherogenic dyslipidemia
    • Raised blood pressure
    • Insulin resistance
    • Proinflammatory state
    • Prothrombotic state

     

    Therapeutic Food protocol for Metabolic Syndrome:

    • Beta Glucan High Potency Synbiotic - 1 heaping tbl BID before 2 largest meals.
    • No. 7 Systemic Booster - 1 tsp before bed. 
    • Be Regular - 2 heaping tbl taken as a meal replacement three times a week.
    • Phyto Power - 2 capsules daily.
    • Chromium, Bio-organic with Beet - 1 capsule BID.

     

    Food Science:

    How can Therapeutic Foods help in the challenge to reduce of the above risk factors?

    There is a multitude of research that strongly makes the point that as dietary fiber goes up the risk of Metabolic Syndrome goes down (Grooms, 2013). Beta Glucan Synbiotic, No. 7 Systemic Booster, Be Regular, and the Phyto Power together contain powerful soluble and insoluble fibers.  Click on their links to see more.

    How does fiber do this?  It helps get rid of excess bile, feeds our good gut bacteria which enhances our SCFA production and reduces cholesterol synthesis, reduces macronutrient absorption, low energy density, gastric distension and increase satiety, delayed gastric emptying, effect on gut hormones, reduced post prandial responses.  All of this collectively helps to control body weight, cholesterol, blood sugar and blood pressure (Satija, 2012).

    Reducing chronic inflammation is of course the major factor for reducing the above risks and the friendly probiotics, rich assortment of phyto nutrients (i.g. flavonoids,etc) in Beta Glucan Synbiotic, Be Regular, Phyto Power and No. 7 all makes this possible (Pan, 2010).

    Bibliography:

    • Ford et al. (2014). Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idopatahic constipation: sytematic review and meta-analysis. AM J Gastroenterol; 109(10): 1547-61.
    • Grooms et al. (2013). Dietary Fiber Intake and Cardiometablic Riks among US Adults: NHANES 1999-2010. Am J Med; 126(12): 1059-1067.
    • Pan et al. (2010). Anti-inflammatory activity of natural dietary flavonoids. Food Funct; 1: 15-31.
    • Satija A, Hu FB. (2012). Cardiovascular Benefits of Dietary Fiber. Curr Atheroscler Rep; 14:505-514.

    Yours,

    Seann Bardell

    We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please  use our products under the advisement of your doctor.

     

    Green Facts:

    Globe_Home 3

    Michael Gregor maintains in Metaboic Syndrome and  Plant Based Diets that eating vegetarian cuts the odds of having metabolic syndrome by more than half.  Check out this 2 minute video.
  • Crohn's Disease

    Dear Friends

    Crohn's Disease is thought to result from a complex interactions between environmental factors, the gut microbes, the genetic background of the patient, and their immune system. It is an autoimmune condition where the patient's immune system attacks their own intestines.  It was a condition virtually unheard of a century ago (Martzaris, 2014).

    Therapeutic Foods protocol for Crohns:

    • LactORN - 1 level tsp twice a week.
    • Supernatant Synbiotic - 1 capsule daily.
    • Phyto Power- 2 capsules daily.

    When you take the LactORN let the powder dissolve in your mouth, that way you get the full effect of its immune modulating oligoribonucleotides (ORNs) from its L. casei.

    Food Science:

    The interaction of commensal bacteria with the intestinal immune system is an essential factor in the development of inflammatory bowel disease.
    Liopis et al., (2009) investigaged the immune responses to signals from the E. coli and the probiotic L. casei in Crohn's disease mucosa.  E. coli significantly upregulated expression of a multitude of inflammatory cytokines (TNF-a, IFN-y, IL-2, IL-6, IL-8 and CXCL 1); while the L. casei downregulated these.
    What's very exciting is that when the two bacteria were combined in an experiment the L. casei prevented and counteracted the proinflammatory effects of E. coli.Both the LactORN and the Supernatant Synbiotic supply L. casei.  We are calling these two products the next generation probiotics.  Click on their links to find out why.
    Pan et al., (2010) reviewed the current knowledge and underlying mechanisms on anti-inflammatory activities of flavonoids; and our Phyto Power contains an exceptionally powerful array of such phytonutrients from wild-crafted blueberries, rosehips, and dandelions from Alaska.  Their multitude of flavonoids additionally offer indirect protection by activating endogenous defense systems and by modulating cellular signaling processes such as reducing NF-kB, enhancing glutathione biosynthesis, Nrf2 and much more.
    Bibliography:
    • Liopis et al. (2009). Lactobacillus casei downregulates commensals' inflammatory signals in Crohn's disease mucosa. Inflamm Bowel Dis; 15(2):275-83.
    • Mantzaris GJ. (2014). When can we cure Crohn's? Best Pract Res Clin Gastroenterol; 28(3): 519-29.
    • Pan et al. (2010). Anti-inflammatory activity of natural dietary flavonoids. Food Funct; 1: 15-31.
    Yours,

    Seann Bardell

    We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please  use our products under the advisement of your doctor.

     

    Green Facts:

    Globe_Home 3

    Michael Gregor in his video, Preventing Crohn's Disease with Diet, sites a fascinating study from Japan where the researchers took a group of Crohn patients in remission, dividing them into two groups, telling one to eat no animal meat and letting the other eat in their normal way. They followed them for 2 years. After two year 92% of those following the vegetarian diet had no relapse where only 20% of the other group remained symptom free. 
  • Be Regular- every day

    Dear Friends

    Constipation is the most common gastrointestinal complaint in the United States.  Nearly 60 million Americans suffer from chronic constipation.

    Be Regular, strongly supports the establishment of a healthy daily bowel movement.

    Be Regular

    Comprised of five organic indigenous whole seeds (chia, buckwheat, amaranth, quinoa, and millet- all gluten free); milled through a patented heat-shearing technology that gently cooks the seeds, making their constipation relieving fibers and life giving nutrients exceptionally available. Be Regular provides fiber, stimulates your colon, and eases constipation.

    Therapeutic Food protocol for constipation:

    • Be Regular - 1-2 heaping tablespoons daily.
    • Beta Glucan Synbiotic - 1 heaping tablespoon daily
    • Phyto Power- 2 capsules
    • No. 7 Systemic Booster- 1 teaspoon

     

    In the morning, add Be Regular (2 heaping Tbl) and Beta Glucan Synbiotic (1 heaping Tbl) to a large glass of water and drink it down while taking the 2 capsules of Phyto Power. You may add a little juice of your choice, such as organic pineapple, apple, pear, or any berry.  Be creative, turn it into a smoothy, it can be your morning breakfast if you choose.  In the evening before bed take a Tsp of the No. 7 Systemic Booster.

    Scientific References:
    • Bianchi et al. (2010). Ability of a high-total antioxidant capacity diet to increase stool weight and bowel antioxidant staus in human subjects. British Journal of Nutrition; 104:1500-1507.
    • Sanjoaquin et al. (2004). Nutrition and lifestyle in relation to bowel movement frequency: a cross-sectional study of 20,630 men and women in EPIC- Oxford. Public Health Nutr; 7(1):77-83.
    • Schmier et al. (2014). Cost savings of reduced constipation rates attributed in increased dietary fiber intakes: a decision-analytic model. BMC Pulic Health; 14:374.

     

    Yours,

    Seann Bardell

    We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please  use our products under the advisement of your doctor.

     

    Green Facts:

    Globe_Home 3The power of Therapeutic Foods is that they are multidimensional in their medical benefits.  So while we are focusing on more fiber here to reduce constipation, by bringing in more fiber through the above fruits, vegetables, seeds and cereals we are also supplying proteins, lipids, vitamins, minerals, antioxidants, and secondary metabolites.  The simple truth is that plant based diets increase regularity—see The Five-To-One Fiber Rule.

  • Weight-less: the new No. 4

    Dear Friends

    To lose weight one needs to reduce the glycemic load within their diet and turn on their fat burning metabolic pathways for energy production.

    Weight - Less, the enriched No. 4 Systemic Booster beautifully supports the goals to balance our metabolism and burn fat (Roy et al., 2011; Paradis et al., 2011; Zenk et al., 2007). The formula is intelligent, effective, and energizing, a winning combination for weight loss.
    Weight-less jpeg

    The research on the ingredients in this product is down right exciting for blood sugar regulation and weight loss.  It also increases energy, cognition, and immune function.

    Take 1 capsule twice daily before your two largest meals. You may take one cap in the morning (upon waking up) to energize your day.

    The Weight - Less No. 4 Booster is comprised of two wildcrafted brown seaweed polyphenol extracts, shown to reduce the post-meal blood sugar levels by almost 50%. This mechanism supports the reduction of the risks of prediabetes, diabetes, obesity and metabolic syndrome.  It reduces insulin levels and increases insulin sensitivity.

    7-Keta is a powerful hormonal metabolite which activates three thermogenic enzymes that turn on fat burning pathways in the mitochondria.  In clinical trials is enabled three times more weight loss that diet and exercise alone.

    A Therapeutic Food whole protocol to support weight loss:

    • Weight-less- one cap daily before two largest meals.
    • Be Regular - 1-2 heaping tablespoons daily.
    • Beta Glucan Synbiotic - 1 heaping tablespoon daily
    • Phyto Power - 1-2 caps daily
    Scientific References:
    • Roy et al. (2011). The effect of commercially-available algal phlorotannins extract on digestive enzymes and carbohydrate absorption in vivo.  Published by Research International.
    • Paradis et al. (2011). A randomized crossover placebo-controlled trial investigating the effect of brown seaweed (Ascophyllum nodosum) and Fucus vesiculosus) on postchallenge plasma glucose and insulin levels in men and wormen. Appl Physio Nut & Metab; 36(6):913-918.
    • Zenk et al. (2007). HUM 5007, a novel combination of thermogenic compounds, and 3-acetyl-7-oxo-dehydroepiandrosterone: each increases the resting metabolic rate in overweight adults. Jrnl of Nut Bio; 18(9):629-634.

     

    Yours,

    Seann Bardell

    We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please  use our products under the advisement of your doctor.

     

    Green Facts:

    Globe_Home 3Fed Up exposes the bitter truth about sugar and American's obesity problem.

    The typical North American diet brings over 130 pounds of added sugars every year.  Recommended annual intake from the American Heart Association is 22 pounds.

  • Detoxification and Therapeutic Foods

    Dear Friends

    Dr. George Kessler, Dr. Artemis Morris, and myself have started to work on a Therapeutic Food’s protocol book.

    This first protocol from Dr. Kessler and myself is designed to support the detoxification process.

    In today’s modern world we battle a monster, which is the underlying cause or at least a contributing factor of many or most of our health problems.  It can make us express or create genetic weakness, feel ill in numerous ways and create the diseases of modern life.  I am, of course, referring to environmental toxins, the bane of modern civilization.

    A Therapeutic Food protocol to support detoxification:

     

    Scientific Rational:

    Excessive exposure to toxic heavy metals or persistent organic pollutants (POPs) from diet or environment is inevitable amid [our present energy based] industrialization and [the subsequent] pollution.  Understanding of the detoxification ability amongst nutrients in plant based food offers therapeutic and preventive effects against these toxins (Chung, 2015).

    Garlic prevents methyl mercury-induced cytotoxicity in peripheral blood leukocytes (Abdalla, 2010), and protects against methyl mercury neurotoxicity in the brain (Belle, 2009). Garlic prevents cadmium-induced kidney damage and decreases the oxidative damage due to lead in rats (Suru, 2008); as well as reduces tissue lead concentrations (Senapati, 2001).

    Chlorella supports the detoxification of polycyclic aromatic hydrocarbons (Yang et al., 2015) and inorganic mercury (Wu & Wang, 2014). Researchers investigated the influence of Chlorella on the excretion and tissue accumulation of methylmercury in mice.  The reduction of Hg levels in the kidney and brain were significant (Siao, 2011).

    Phyto Power with its combination of wild-crafted rosehip, blueberry and dandelion supports the shifting of the body’s reserves to become more alkaline which enhances its ability to detoxify (Minich, 2007). Denev et al., (2014) found rosehips and blueberries to supply the most potent inhibitors for lipid peroxidation.

    Beta Glucan High Potency Synbiotic contains powerful pedigreed strains of Lactobacillus and Bifidobacterium species. Research demonstrates that probiotic supports the binding of lead and cadmium to their cell surface and hold on to them through defecation.  Singh and Sharma (2010) showed that L. acidophilus was able to bind and remove arsenic found in drinking water.  Robinson and Tuovinenn (1984) demonstrated that L. rhamnosus reduces the bioaccumulation of mercury and arsenic in pregnant women and children.  Shrivastava et al. (2003) found that Lactobacilli can transform chromium (CrVI) to its less toxic form (CRIII). The fibers and probiotic combination in the Beta Glucan support the regularity of the GI tract to remove toxins and help those with IBS or other gastrointestinal disorders (Lacey at al., 2015; Sarowska et al., 2013).

    Cruciferous vegetables contain secondary metabolites termed glucosinolates that break down to products that upregulate hepatic detoxification enzymes.  These enzymes are called phase II enzymes and are responsible for phase II liver detoxification—a critical component in the body’s detoxification processes (Nho CW, Jeffery E., 2001).  Our cruciferous sprouts magnify production of the glucosinolates 100 fold.

    References:

    • Abdalla et al. (2010). Allium sativum L. extract prevents methyl mercury-induced cytotoxicity in peripheral blood leukocytes (LS). Food and Chemical toxicology; 48(1): 4147-421.
    • Belle et al. (2009). Comparative Evaluation of Adenosine Deaminase Activity in Cerebral cortex and Hippocampus of young and Ault Rats: Effect of Garlic Extract (Allium sativum L.) on their Susceptibility to Heavy Metal Exposure. BCPT; 104(5): 408-413.
    • Chung R.T. (2015). Detoxification effects of phytonutrients against environmental toxicants and sharing of clinical experience on practical applications. Environ Sci Pollut Res; doi:10.1007/s 11256-015-5263-3.
    • Denev at al. (2014) Biological activities of selected polyphenol-rich fruits related to immunity and gastrointestinal health. Food Chem; 157: 37-44. doi: 10.1016/j.foodchem.2014.02.022.
    • Haittunen et al. (2007) Rapid removal of lead and cadmium from water by specific lactic acid bacteria. Nit J Food Microbiol; 114:30-35.
    • Lacey at al. (2015). New and emerging treatment options for irritable blowel syndrome. Gastroenterol Hepatol (NY); 11(4) (suppl 2); 1-9.
    • Minich D. M, Bland L. S. (2007). Acid-alkaline balance: role in chronic disease and detoxification. Altern Ther Health Med; 13(4): 62-5.
    • Nho CW, Jeffery E. (2001). The Synergistic Upregulation of Phase II Detoxification Enzymes by Glucosinolate Breakdown Products in Cruciferous Vegetables. Tox and Appl Pharm; 174(2):146-152.
    • Robinson J. B, Tuovinen OH. (1984). Mechanisms of microbial resistance and detoxification of mercury and organomercury compounds: physiological, biochemical, and genetic analyses. Microbiol Rev; 48:95-124.
    • Sarowska et al. (2013). The therapeutic effect of probiotic bacteria on gastrointestinal disease. Adv Clin Exp Med; 22(5): 759-66.
    • Senapati et al. (2001). Effect of garlic (Allium sativum L.) extract on tissue lead level in rats. J Ethnopharmacol; 76(3): 229-32.
    • Shrivastava et al. (2003). Various cells of the immune system and intestine differ in their capacity to reduce hexavalent chromium. FEMS immunol med microbio; 38:65-70.
    • Singh et al. (2010). Removal of arsenic (III) from wastewater using Lactobacillus acidophilus. Bioremediat j; 14:92-97
    • Suru S. M. (2008). Onion and garlic extracts lessen cadmium-induced nephrotoxicity in rats. Biometals; 21(6): 623-33.
    • Wu Y, Wang W. X. (2014). Intracellular speciation and transformation of inorganic mercury in marine phytoplankton. Aquat Toxicol; 148:122-9.
    • Yang et al. (2015). Epigenetic modulation of Chlorella (Chlorella vulgaris) on exposure to polycyclic aromatic hydorcarbons. Environ Toxicol Pharmacol; 40(3): 758-63.
    •  
    Yours,

    Seann Bardell

    We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please  use our products under the advisement of your doctor.

     

    Green Facts:

    Globe_Home 3
    The Environmental Working Group empowers people to live healthier lives in a healthier environment.  With breakthrough research and education they drive consumer choice and civic action.

  • The Missing Fiber

    Dear Friends

    As dietary fiber goes up the risk of Metabolic Syndrome goes down!

    The greater our dietary fiber intake is, the more we reduce the risk for Type 2 Diabetes, cardiovascular disease, certain cancers, weight gain, obesity and diverticular disease as well as constipation (Grooms, 2013).

    The average American intake is about ½ of what it should be with the guidelines for dietary fiber from the American Heart Association and the Institute of Medicine being at 30g/day (King, 2013).

    Two BioImmersion Therapeutic Foods help to increase your dietary fiber:

    Beta Glucan High Potency Synbiotic and Energy Sustain.  See Clinical Notes.

    References:

    • King et al. (2012). Trends in dietary fiber intake in the United States, 1999-2008. J Acad Nutr Diet;112(5):642-8.
    • Grooms et al. (2013). Dietary Fiber Intake and Cardiometabolic Risk among US Adults: NHANES 1999-2010. Am J Med;126(12):1059-1067.
    Yours,

    Seann Bardell

    We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please  use our products under the advisement of your doctor.

    Clinical NotesBG and ES 4

    Here's to our health:

    Take one heaping tablespoons of the Beta Glucan daily and two--three heaping tablespoons of the Energy Sustain at least three times a week. Combine the two and make a smoothie as a meal replacement.  With this kind of dosing you will be adding around 10 grams of fiber.  And other wonderful life enhancing
    nutrients (see the links above and below).

    To make a great smoothie, add to the Beta Glucan and Energy Sustain some fresh fruit, protein powder, and flax seed. We can easily get to 20 grams with the added fiber.

    Green Facts:

    Globe_Home 3Here is your free online Permaculture Design Course with World-Class Sustainability Teachers.  Perhaps in 2016 we can all get involved in some way with Permaculture.

    Happy New Year! 
  • HAPPY HOLIDAYS

    Dear Friends

    Happy Holidays to each and every one of you!!!  Thank you for being our friends and our cherished customers.  May next year be a wonderful year for us all.

    Sincerely yours,

    Seann and Dohrea Bardell

    Clinical Notes

    Here's to your health:

    Carrots

     

     

     

     

     

     

     

     

     

     

     

     

     

    Green Facts:

    Globe_Home 3Here is your free online Permaculture Design Course with WorldClass Sustainability Teachers.  Perhaps in 2016 we can all get involved in some way with Permaculture.

    Happy New Year! 

  • Inflammation, Diseases, & No. 7 Booster

    Dear Friends,

    Chronic inflammation is a key risk factor to the growing degenerative diseases we are facing today.

    The No. 7 Systemic Booster is a foundational product that potentiates many protocols as it is designed to support multiple systems in our body's ability to overcome chronic inflammation.  Think of the foods, fiber, and probiotics in the No 7 as a communication switchboard that directs the different items in your protocols toward their therapeutic goal. That is the power of foods acting epigenetically (Han. 2007).

    No.7 2Research on the effects of foods and probiotics found in the No 7 is exciting.

    Liopis (2009) research demonstrated L. casei's abilitiy to downregulate inflammatory signals (TNF-alpha, IFN-gamma, IL-2, IL-6, IL-8, and CXCL 1) in Crohn's disease mucosa. The researchers conclusion was that live L. casei can counteract the proinflammatory effects of E. coli on CD inflamed mucosa.

    Ford (2014) meta-analysis on the efficacy of prebiotics, probiotic and synbiotics in IBS and CIC (the mean number of stools per week) found that probiotic had beneficial effects on global IBS, abdominal pain, bloating and flatulence.  Their conclusion: probiotics are effective treatments for IBS. Their degrees of effectiveness depending on the species and strains.

    The No. 7's bacteria strains and the supernatant were chosen by our Bulgarian scientists for their effectiveness supporting the inhibition of Clostridial species, as overgrowth of Clostridia is found to create a serious GI tract inflammatory problem (Kounev 2007).  The inulin, berries and fruit provides the prebiotic for the inflammatory reducing-strain of acidophillis, casei and longum.  Inulin is very bifidogenic.

    Fruit and berry polyphenols provide a myriad anti-inflammatory actions.  They perform as anti-oxidants, anti-inflammatories, anti-microbials, they protect against the diseases of aging.  They are also hormetic, that is they behave like hormones, epigenetically activating endogenous defense systems (Han. 2007).

    Lapshina (2015) demonstrated that the flavonoids in cranberry prevent toxic rat liver mitochondrial damage in vivo and scavenge free radicals in vitro.  They scavenged nitric oxide radicals, superoxide anion radicals, and hydroxyl radicals.  Novotny (2015) showed that cranberry juice consumption lowers markers of cardiometabolic risk including CRP.

    Colombo's (2013) research demonstrated the anti-inflammatory activity of pomegranate in the gastrointestinal tract.  Pomegranate is shown to help with gastritis.

    Howatson et al. (2009) determined the efficacy of a tart cherry juice in aiding recovery and reducing muscle damage, inflammation and oxidative stress.  The cherry juice appears to provide a viable means to aid recovery following strenous exercise by increasing total antioxidative capacity, reducing inflammation, lipid peroxidation and so aiding in the recovery of muscle function.  There is much anecdotal evidence for tart cherry reducing the pain of arthritis.

    Regarding the nutriceutical contribution within the No. 7, the Fructo Borate Complex contributes to inflammatory reduction by a variety of mechnisms.  Boron downregulates over zealous immune cells for unloading their oxidative bursts into inflamed joints.  Boron also decreases blood levels of CRP and increases blood levels of Vitamin D3. We also add extra Vitamin D3 to No. 7 at 400 IU per tsp (Scorei et al., 2011).

    Barley Sprout Nucleotides lower the blood sugar levels for hyperglycemics.  Reducing blood sugar levels also reduces blood LDL levels, and lower LDLs reduces the risk for oxidized LDL, a very dangerous inflammatory inducing free radical.

    Lee et al (2015) investigated the effect of L-carnitine supplementation on inflammation markers in patients with CAD.  CRP,IL-6, and TNF- alpha were all significantly lowered.  They suggested the use of L-carnitine supplementation to reduce inflammation in CAD.

    L- Carnosine is an exciting anti-aging molecule, much has been said and researched about it.  In short, carnosine works as an antioxidant to prevent the formation of oxidized sugars, also called Advanced Glycosylation End-products or AGEs. The less AGEs in your body the younger your body feels (Asif et al., 2000).

    References:

    • Liopis et al. (2009). Lactobacillus casei downregulates commensals' inflammatory signals in Crohn's diseases mucosa. inflamm Bowel Dis;15(2):275-83.
    • Ford et al. (2014). Efficacy of prebiotics, probiotics, and synbiotics in irritable bowel syndrome and chronic idiopathic constipation: systematic review and meta-analysis. Am J Gastroenterol;109(10):1547-61.
    • Han et al. (2007). Dietary Polyphenols and their Biological Significance. Int J Mo Sci; 8(9):950-988.
    • Lapshina et al. (2015). Cranberry flavonoids prevent toxic rat liver mitochondrial damage in vivo and scavenge free radicals in vitro. Cell Miochem Funct;33(4):202-210.
    • Novotny et al. (2015). Cranberry juice consumption lowers markers of cardiometabliolic risk, including blood pressure and circulating C-reactive protein, triglyceride, and glucose concentrations in adults. J Nutr;145(6):1185-93.
    • Colombo et al. (2013). A review on the Anti-Inlfammatory Activity of Pomegranate in the Gastrointestinal tract. Evidence-based Complementary and Alternative Medicine;Article ID 247145.
    • Howatson et al. (2009). Influence of tart cherry juice on indices of recovery following marathon. Scandinavian Journal of Med & Sci in Sports;20(6):843-852.
    • Scorei et al. (2011). A double-blind, Placebo-Controlled Polot Study to Evaluate the Effect of Calcium Fructoborate on Systemic Inflammation and Dyslipidemia Markers for Middle-Aged People with Ordinary Osteoarthritis. Biol Trace Elem Res;144:253-263.
    • Lee et al. (2008). Vitamin Deficiency: An important, Common, and Easiiy Treatable Cardiovascual Risk Factor? J Am Coll Cardiol;52(24):1949-1956.
    • Lee et al. (2015). Antiinflammatory effects of L-canitine supplementation (1000 mg/d) in coronary artery disease patients. Nutrition;31(3):475-9.
    • Asif et al. (2000). An Advanced Glycation Endproduct cross-link breaker can reverse age-related increases in myocardial stiffness. Proc Natl Acad Sci USA; 97(6):2809-2813.

     

    Yours,

    Seann Bardell

    We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please  use our products under the advisement of your doctor.

    Clinical Notes

    The No. 7 Systemic Booster is meant to be taken on a regular basic as not only your gastrointestinal probiotic/prebiotic supplement but as your multiple for all of the body's systems—as a anti-inflammatory, healthy aging product.

    The suggested dose is one teaspoon daily.

    No. 7 contains:  probiotics (L. acidophilus, L. casei, B. longum), supernatant (inactive probiotic cells populations of L. bulgaricus, S. thermophilus and their metabolites), whole organic pineapple, organic tart cherry, organic cranberry and extract, organic pomegranate and extract, Fructo Borate Complex, barley sprout nucleotides, inulin (derived from organic chicory root), L-Carnitine, L-Carnosine, Vitamin D-3 and folic acid.

    The Bulgarian probiotics and their Supernatant are exceptional contributors within the army of synbiotic organisms in the gut microbiome towards the reduction of GI tract inflammation.

    Green Facts:

    Globe_Home 3Is not investment into new energy a smart investment, the right investment?  Even before December arrived, 2015 had proven a record breaking year for corporate purchasing of large scale wind and solar energy.
  • Beta Glucan Synbiotic & CHD

    Dear Friends,

    Coronary heart disease's risk factors are high blood pressure, high blood cholesterol, [high triglycerides], obesity, physical inactivity, diabetes and stress (Saini et al., 2010; Serino et al., 2014).

    Beta Glucan High Potency Synbiotic provides oat beta glucan, red beet fiber, chicory fiber (inulin), and probiotics; healthy food ingrediets shown by research to support the reduction in the risk markers for obesity, diabetes and CVD.

    Whitehead et al. (2014) performed a meta-analysis on 28 randomized controlled trial on the  effectiveness of oat bran beta glucans to lower LDL cholesterol.  Oat beta glucan reduced LDL and total cholesterol by 0.25 mmol/L and 0.30 mmol/L respectively at doses of 3g/d.

    Experimental data are convincing in support of the hypothesis that the fiber inulin (prebiotic) inhibit hepatic lipogenesis (formation of cholesterol), inducing a significant hypotriglyceridemic effect (Saini, 2010).

    DiRienzo (2014) reviewed 26 clinical studies and two meta-analyses and found amongst others that L. acidophilus plus inulin significantly decreased LDL cholesterol.  Their conclusion was that probiotic intake as a therapeutic lifestyle change can have a positive effect on reduced CHD risk factors.

    References:

    • Serino et al. (2014). Far from the Eyes, Close to the Heart:  Dysbiosis of Gut Microbiota and Cardiovasuclar Consequences. Curr Cardiol Rep.; 16(11):540.
    • Saini et al. (2010). Potential of probiotics in controlling cardiovascular diseases. J. Cardiovasc Dis Res;1(4):213-214.
    • Whitehead et al. (2014) Cholesterol-lowering effects of oat Beta glucan: a meta-analysis of randomized controlled trials. Am j. Clin. Nutr.;100(6):1413-1421.
    • DiRienzo DB. (2014). Effect of probiotics on biomarkers of cardiovascular disease: implications for heart-healthy diets. Nutr Rev.;72(1):18-29.

    See Clinical Notes for more.

    Yours,

    Seann Bardell

    We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners.  There is a growing body of literature on food based nutrition and supplements and their application in support of our health.  Please  use our products under the advisement of your doctor.

    Clinical Notes

    As you can see the Beta Glucan High Potency Synbiotic contains five powerful lactic acid bacteria and three forms of fiber.  The suggested dose in the research above is 3 grams per day for individuals dealing with high cholesterol and the different risk factors. One tablespoon twice daily before the two largest meals will supply the suggested dosage in the research.

    The red beet root fiber support the increase of good HDL cholesterol.

    All of the soluble fibers in this formula are fermented by these good bacteria into SCFA: butyrate, propionate and acetate.  The butyrate promotes the healing of tight junctions thereby reducing inflammation which is a major risk factor for CVD.  The propionate reduces cholesterol levels.

    BetaGlucan HP

    Green Facts:

    Globe_Home 3How did the Paris 2015 Climate Change talks go?  "By comparison to what it could have been, it's a miracle.  By comparison to what it should have been, it's a disaster."A Beginner's guide to what transpired at the Paris climate summit.

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