Anthocyanins Effect on Endothelial Vascular Function: Better Cognition, Stronger Heart
I get very excited when I read new research articles that emphasize the power of food used therapeutically.
And yes, the mechanism is complex, and it takes me time to understand how polyphenols actually affect the health of our heart and brain. It is worth reading.
Scientists are studying the connection between anthocyanins (part of polyphenols) on cognition and vascular function. In particular, the endothelial vascular effects from polyphenols.
Ellis et al., (2024) recent Systemic review examines 1486 controlled studies, from which 20 were selected, to assess the effect of anthocyanins on vascular function and cognition.
The conclusion of the review is positive - anthocyanins improve cognition and cardiovascular health.
The intervention with anthocyanins was simple: participants received a capsule of either freeze-dried powder, extracts or concentrates, from blueberries, blackcurrant, berry mix, or grape juice and others. The researchers in the various studies measured blood pressure, administered cognitive tests (e.g., memory, attention, language, etc.), neuronal protein, nerve growth factor, and endothelial function by using 'flow mediated dilation' (FMD).
Both short and longer terms studies were performed (or to use the researchers' words, acute and chronic studies), and some found a reduction in anxiety alongside cognitive improvements. The dosage can be higher for faster results and lower for the accumulative effect.
Do keep in mind that to get the best results, the gut has to break down these larger molecules for optimal absorption. To be able to perform this task we need a health microbiome. The good news is that probiotics love polyphenols, it is the perfect food that allows them to flourish and grow, which is exactly what is necessary for our health.
The mechanics of the how all this happens is worth reading (Article). I have included the Blueberry Extract as Seann formulated this amazingly powerful, 12% anthocyanin mix with Dr. James Joseph, a leading scientist on brain health, with a team that continues on his innovative work.
Enjoy!
Yours as always,
Dohrea
References
We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.
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