High ORAC Synbiotic Formula

The High ORAC Synbiotic Formula is an exceptional product and unique in the market today. One capsule a day provides a rich blend of berry extracts and whole fruit, as well as our renowned pedigreed probiotics, plus organic chicory fiber.

Providing a rich diversity and potent concentration of the critically important and medically recognized berry and fruit bioflavonoids, plus offering high potency levels of two important genera of pedigreed probiotic organisms makes for a perfect daily supplement.

Take one capsule a day.


$71.40

Availability: Temporarily unavailable

Description

Details

25 billion cfu/cap of certified strains of pedigreed probiotic with Therapeutic Foods in a synbiotic formula of L. acidophilus, B. longum, and 250 mg wild blueberry extract, grape and grape seed extract, raspberry and raspberry seed extract, wild bilberry extract, cranberry, tart cherry and prune plus 250 mg of inulin derived from chicory fiber.

Advanced freeze-drying technology. 1500 ORAC/cap. 60 caps/bottle. 500 mg/ cap.

No excipients.

  • Combination of Green Technology for highest phytonutrient potential and Microbiome Technology for pure cultures of pedigreed strains of standardized referenced material with Original molecular identity confirmed routinely by DNA sequencing.
  • Berry extracts and Fruit- 250mg of pure freeze dried Wild Blueberry extract, Grape and Grape Seed extract, Raspberry and Raspberry Seed extract, Wild Bilberry extract, Cranberry, Tart Cherry and Prune.
  • 250mg of inulin from chicory fiber.
  • 25 billion of Original strains of Lactobacillus acidophilus and Bifido longum.
  • Designed for inflammatory conditions in the GI tract and to fulfill the 5-9 fruits and vegetable campaign for phytonutrients and ORAC values.
  • Potent antioxidant with high ORAC of 1500 units per capsule (5-9 fruits and vegetables a day provides 1800 to 2500 ORAC units).
  • Original strains selected to protect, counteract and neutralize dietary toxins, mutagens, carcinogens and infectious organisms.
  • Detoxifies dietary mycotoxins, enterotoxins, exotoxins and carcinogens.
  • Reduces inflammation systemically and throughout the gastrointestinal system: Original strains in conjunction with Wild Blueberry Extract, Grape and Grape Seed extract, Raspberry Seed extract, Tart Cherry, Prune.
    • Preservation of stem cells.
    • Cardiovascular health
  • Regeneration of the enteric nervous system: Wild Blueberry, Wild Bilberry.
  • Broad spectrum antimicrobial: Original strains in conjunction with Raspberry Seed extract, Wild Blueberry Extract, Grape Seed extract, Cranberry.
  • Vision: Wild Blueberry Extract, Wild Bilberry extract
  • No fillers, flowing agents or excipients of any kind.
  • Read monograph in the web library.
Research

Research

BIBLIOGRAPHY

Berries and Human Health

Seeram, N.P. (2014). Berries and human health: research highlights from the Fifth Biennial Berry Health Benefits Symposium. J Agric Food Chem, 62(18), 3839-41.

Seeram, N.P. (2012). Emerging research supporting the positive effects of berries on human health and disease prevention. J Agric Food Chem, 60(23), 5685-6.

Seeram, N.P. (2008). Berry fruits: compositional elements, biochemical activities, and the impact of their intake on human health, performance, and disease. J Agric Food Chem, 56(3), 627-9.

The Bioavailability of Anthocyanin For Health

Lila, M.A., Burton-Freeman, B., Grace, M., & Kalt, W. (2016). Unraveling Anthocyanin Bioavailability for Human Health. Annu Rev Food Sci Technol,7, 375-93. doi: 10.1146/annurev-food-041715-033346.

Sandhu, A.K., Huang, Y., Xiao, D., Par, E., Edirisinghe, I., & Burton-Freeman, B. (2016). Pharmacokinetic Characterization and Bioavailability of Strawberry Anthocyanins Relative to Meal Intake. J Agric Food Chem, 64(24), 4891-9. doi: 10.1021/acs.jafc.6b00805.

Berry Fruit and Cancer Support

Li, L., Adams, L.S., Chen, S., Killan, C., Ahmed, A., & Seeram, N.P. (2009). Eugenia jambolana Lam. [purple berries] berry extract inhibits growth and induces apoptosis of human breast cancer but not non-tumorigenic breast cells. J Agric Food Chem, 57(3), 826-31.

Seeram, N.P. (2010). Recent trends and advances in berry health benefits research. J Agric Food Chem, 58(7), 3869-70.

Seeram, N.P. (2008). Berry fruits for cancer prevention: current status and future prospects. J Agric Food Chem, 56(3), 630-5.

Seeram, N.P., Adam, L.S., Zhang, Y., Lee, R., Sand, D., Scheuller, H.S., & Heber, D. (2006). Blackberry, black raspberry, blueberry, cranberry, red raspberry, and strawberry extracts inhibit growth and stimulate apoptosis of human cancer cells in vitro. J Agric Food Chem, 54 (25), 9329-39.

Berries and Cognitive Support

Andres-Lacueva, C., Shukitt-Hale, B., Gall,i R.L., Jauregui, O., Lamuela-Raventos, R.M., & Joseph, J.A. (2005) Anthocyanins in aged blueberry-fed rats are found centrally and may enhance memory. Nutr Neurosci, 8, 111-120.

Bickford, P., Gould, T., Briederick, L., Chadman, K., Pollock, A., Young, D., Shukitt-Hale, B., Joseph, J. (2000) Antioxidant-rich diets improve cerebellar physiology and motor learning in aged rats. Brain Res, 866, 211-217.

Carey, A.N., Gomes, S.M., Shukitt-Hale, B. (2014) Blueberry supplementation improves memory in middle-aged mice fed a high-fat diet. J Agric Food Chem, 62:3972-3978.

Casadesus, G., Shukitt-Hale, B., Stellwagen, H.M., Zhu, X., Lee, H.G., Smith, M.A., & Joseph, J.A. (2004) Modulation of hippocampal plasticity and cognitive behavior by short-term blueberry supplementation in aged rats. Nutr Neurosci, 7, 309-316.

Cherniack, E.P. (2012). A berry thought-provoking idea: the potential role of plant polyphenols in the treatment of age-related cognitive disorders. British Journal of Nutrition, 107, 1–7.

Devore, E.E., Kang, J.H., Breteler, M.M., & Grodstein, F. (2012). Dietary intakes of berries and flavonoids in relation to cognitive decline. Ann Neurol, 72(1), 135-43.

doi: http://dx.doi.org/10.1002/ana.23594

Essa, M.M., Vijayan, R.K., Castellano-Gonzalez, G., Memon, M.A., Braidy, N., & Guillemin, G.J. (2012). Neuroprotective effect of natural products against Alzheimer's disease. Neurochem Res, 37(9), 1829-42. doi: 10.1007/s11064-012-0799-9.

Loef, M., Walach, H. (2012). Fruit, vegetables and prevention of cognitive decline or dementia: a systematic review of cohort studies. J Nutr Health Aging, 16(7), 626-30.

Krikorian, R., Nash, T.A., Shidler, M.D., Shukitt-Hale, B., & Joseph, J.A. (2010). Concord grape juice supplementation improves memory function in older adults with mild cognitive impairment. British Journal of Nutrition, 103(5), 730–4.

Shukitt-Hale, B., Lau, F.C., Joseph, J.A. (2008). Berry fruit supplementation and the aging brain. Journal of Agricultural and Food Chemistry, 56, 636–641.

Wang, J., Ferruzzi, M.G., Ho, L., Blount, J., Janie, E.M., Gong, B., … Pasinettie, G.M. (2012). Brain-targeted proanthocyanidin metabolites for Alzheimer's disease treatment. Journal of Neuroscience, 32(15), 5144–5150.

Anthocyanin and Neurological Support

Strathearn, K.E., Youself, G.G., Grace, M.H., Tambe, M.A., Ferruzzi, M.G., Wu, Q.L., … Rochet, J.C. (2014). Neuroprotective effects of anthocyanin- and proanthocyanidin-rich extracts in cellular models of Parkinson ׳s disease. Brain Res, 1555, 60-77.

Subash, S., Essa, M.M., Al-Adaw, S., A Memon, M., Manivasagam, T, & Akbar, M. (2014). Neuroprtective effects of berry fruits on neurodegenerative diseases. Neural Regeneration Research, 9(16), 1557-15566.

Berries and Heart Health

Basu, A., Rhone, M., & Lyons, T.J. (2010) Berries: emerging impact on cardiovascular health. Nutr Rev, 68,168-177

Anti-Aging and Oxidative Balance with Phenolic Rich Berries and Fruit

Burton-Freeman, B. (2010). Postprandial metabolic events and fruit-derived phenolics: a review of the science. Br J Nutr, 104 (3), S1-14. doi: 10.1017/S0007114510003909.

Joseph, S.V., Edirisinghe, I., & Burton-Freeman, B.M. (2016). Fruit Polyphenols: A Review of Anti-inflammatory Effects in Humans. Crit Rev Food Sci Nutr, 56(3), 419-44. doi: 10.1080/10408398.2013.767221.

Lau, F.C., Shukitt-Hale, B., & Joseph, J.A. (2007). Nutritional intervention in brain aging: reducing the effects of inflammation and oxidative stress. Subcell Biochem, 42, 299-318.

Grape Seed Extract and Blood Pressure Support

Edirisinghe, I., Burton-Freeman, B., & Tissa, Kappagoda, C. (2008). Mechanism of the endothelium-dependent relaxation evoked by a grape seed extract. Clin Sci (Lond), 114(4), 331-7.

Park, E., Edirisinghe, I., Choy Y.Y., waterhouse, A., Burton-Freeman, B. (2016). Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial. Br J Nutr, 115(2), 226-38. doi: 10.1017/S0007114515004328

Strawberries and Metabolic Syndrome [Obesity] Support

Park.E., Edirisinghe, I., Wei, H., Vijayakumar, L.P., Banaszewski, K., & Burton-Freeman, B. (2016). A dose-response evaluation of freeze-dried strawberries independent of fiber content on metabolic indices in abdominally obese individuals with insulin resistance in a randomized, single-blinded, diet-controlled crossover trial. Mol Nutr Food Res , 60(5), 1099-109. doi: 10.1002/mnfr.201500845.

Strawberries and Heart Health

Edirisinghe, I., Burton-Freeman, B., Varelis, P., & Kappagoda, T. (2008).Strawberry extract caused endothelium-dependent relaxation through the activation of PI3 kinase/Akt. J Agric Food Chem, 56 (20), 9383-90. doi: 10.1021/jf801864t.

Jenkins, D.J., Nguyen, T.H., Kendall, C.W., Faulkner, D.A., Bashyam, B, Kim, I.J., … Singer, W. (2008). The effect of strawberries in a cholesterol-lowering dietary portfolio. Metabolism, 57(12), 1636-44. doi: 10.1016/j.metabol.2008.07.018.

Red Raspberries and Heart Health

Burton-Freeman, B.M., Sandhu, A.K., & Edirisinge, I. (2016). Red Raspberries and Their Bioactive Polyphenols: Cardiometabolic and Neuronal Health Links. Adv Nutr, 7(1):44-65. doi: 10.3945/an.115.009639.

Berries and Metabolic Syndrome Support

Basu, A., & Lyons, T.J. (2012). Strawberries, blueberries, and cranberries in the metabolic syndrome: clinical perspectives. J Agric Food Chem, 60: 5687-92.

Ingredients

Ingredients

One Vegetarian Capsule Contains:
L. acidophilus, B. longum 25billion CFU 
Mixed berries &fruits (251:1) 250mg 
  Wild Blueberry Extract 
  Grape and Grape Seed Extract 
  Raspberry & Raspberry Seed Extract 
  Cranberry 
  Prune 
  Tart Cherry 
  Wild Bilberry Extract 
Inulin (from chicory root) 250mg

Other ingredients: cellulose & water (capsule shell)

Suggested Use

Suggested Use

1 capsule daily or as directed by your healthcare practitioner

Reviews