Glucosinolates & Sulforaphanes: It is Time to Tune In

If you have not paid attention to Glucosinolates & Sulforaphanes, it is time to tune in and experience a true powerhouse.

Glucosinolates & Sulforaphanes is a mix of Organic Broccoli Sprouts - one of the highest potency on the market.   Glucosinolates - 15,000ppm, Glucoaphanin - 10,000ppm, and Sulforaphanes Potential of 4,000ppm. 

And it works hard for you. 

Broccoli sprouts are known in research to offer a gentle and effective liver detox,  DNA repair, protection against all sorts of cancers, cardiovascular health, gut health, and brain health. 

In 1992, Zhang et al. have isolated sulforaphane and shown that it is a potent and effective anti-carcinogenic agent (Zhang et al., 1992; Leon et al., 2017). Since then, Sulforaphanes (SFN) derived from cruciferous broccoli sprouts have shown numerous bioactivities (Su et al., 2018) that offer different kinds anti-carcinogenic properties (Mokhtari et al., 2018; Suresh et al., 2018; Su et al., 2018), phase II detoxifying enzymes (Thangapandiyan et al., 2018; James et al., 2012), including phase II antioxidant enzymes in the human upper airways (Riedl et al., 2009; Heber et al., 2014).

Moreover, SFN has also been researched as an effective agent for cardiovascular health (Gray, 2018; Angeloni et al., 2009), anti-inflammation (López-Chillón et al., 2018), detoxification of airborne pollutants (Egner et al., 2014), H-pylori antimicrobial with a general benefit for gut health (Yanaka, 2017, and 2018) and brain health (Sedlak et al., 2017), including support for autism (Singh et al, 2014). 

Check out the research on our research tab for the Glucosinolates & Sulforaphanes, it is impressive. 

Each of our vegan capsule has 500 mg of organic broccoli sprouts, harvested at the peak of their phytonutrient power. 

References:

• Angeloni, C., Leoncini, E., Malaguti, M., Angelini, S., Hrelia, P., & Hrelia, S. (2009). Modulation of phase II enzymes by sulforaphane: implications for its cardioprotective potential. Journal of agricultural and food chemistry, 57(12), 5615-5622.
• Egner, P. A., Chen, J. G., Zarth, A. T., Ng, D., Wang, J., Kensler, K. H., ... & Fahey, J. W. (2014). Rapid and sustainable detoxication of airborne pollutants by broccoli sprout beverage: results of a randomized clinical trial in China. Cancer prevention research, canprevres-0103.
• Gray, S. G. (2018). The Potential of Epigenetic Compounds in Treating Diabetes. In Epigenetics in Human Disease (Second Edition) (pp. 489-547).
• Heber, D., Li, Z., Garcia-Lloret, M., Wong, A. M., Lee, T. Y. A., Thames, G., ... & Nel, A. (2014). Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles. Food & function, 5(1), 35-41.
• James, D., Devaraj, S., Bellur, P., Lakkanna, S., Vicini, J., & Boddupalli, S. (2012). Novel concepts of broccoli sulforaphanes and disease: induction of phase II antioxidant and detoxification enzymes by enhanced-glucoraphanin broccoli. Nutrition reviews, 70(11), 654-665.
• Leone, A., Diorio, G., Sexton, W., Schell, M., Alexandrow, M., Fahey, J. W., & Kumar, N. B. (2017). Sulforaphane for the chemoprevention of bladder cancer: molecular mechanism targeted approach. Oncotarget, 8(21), 35412.
• López-Chillón, M. T., Carazo-Díaz, C., Prieto-Merino, D., Zafrilla, P., Moreno, D. A., & Villaño, D. (2018). Effects of long-term consumption of broccoli sprouts on inflammatory markers in overweight subjects. Clinical Nutrition.
• Mokhtari, R. B., Baluch, N., Homayouni, T. S., Morgatskaya, E., Kumar, S., Kazemi, P., & Yeger, H. (2018). The role of Sulforaphane in cancer chemoprevention and health benefits: a mini-review. Journal of cell communication and signaling, 12(1), 91-101.
• Paśko, P., Tyszka-Czochara, M., Galanty, A., Gdula-Argasińska, J., Żmudzki, P., Bartoń, H., ... & Gorinstein, S. (2018). Comparative study of predominant phytochemical compounds and proapoptotic potential of broccoli sprouts and florets. Plant Foods for Human Nutrition, 73(2), 95-100. 
• Riedl, M. A., Saxon, A., & Diaz-Sanchez, D. (2009). Oral sulforaphane increases Phase II antioxidant enzymes in the human upper airway. Clinical immunology, 130(3), 244-251.
• Sedlak, T. W., Nucifora, L. G., Koga, M., Shaffer, L. S., Higgs, C., Tanaka, T., ... & Sawa, A. (2017). Sulforaphane Augments Glutathione and Influences Brain Metabolites in Human Subjects: A Clinical Pilot Study. Molecular neuropsychiatry, 3(4), 214-222. 
• Su, X., Jiang, X., Meng, L., Dong, X., Shen, Y., & Xin, Y. (2018). Anticancer Activity of Sulforaphane: The Epigenetic Mechanisms and the Nrf2 Signaling Pathway. Oxidative Medicine and Cellular Longevity, 2018.
• Suresh, S., Waly, M. I., & Rahman, M. S. (2018). Broccoli (Brassica oleracea) as a Preventive Biomaterial for Cancer. In Bioactive Components, Diet and Medical Treatment in Cancer Prevention (pp. 75-87). Springer, Cham.
• Thangapandiyan, S., Ramesh, M., Miltonprabu, S., Hema, T., Nandhini, V., & Bavithrajothi, G. (2018). Protective Role of Sulforaphane against Multiorgan Toxicity in Rats: An In-vivo and In-vitro Review Study. Research & Reviews: A Journal of Toxicology, 8(1), 1-8.
• Yanaka, A. (2018). Daily intake of broccoli sprouts normalizes bowel habits in human healthy subjects. Journal of clinical biochemistry and nutrition, 62(1), 75-82.
• Zhang, Y., Talalay, P., Cho, C. G., & Posner, G. H. (1992). A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proceedings of the national academy of sciences, 89(6), 2399-2403.

Yours as Always,

Dohrea

We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.

 Research and Our World: Peace 

I thought to share a little bit from my theory on peace: I created a Kantian normative model for peace as a theory that is built for practice. Peace flourishes in enlightened communities because human rights are enacted according to the categorical imperative doctrines of right and virtue (more on that later). Peace does mean the absolute lack of wars between people or states. As an egalitarian phenomenon for the global community, peace is a categorical imperative, a normative law in itself.

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