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Polyphenols and Gut Microbiota Cross-Talk: Prevention & Reversal of Conditions

"In fact, polyphenols can prevent or reverse the progression of disease processes through many distinct mechanism" (Koudoufio et al., 2020).  

Koudoufio's team is not alone in their claim that polyphenols can be that impactful upon our health. Scientists from all over the world are studying polyphenols and their healing mechanisms. 

As it turns out, polyphenols are very communicative in the body. 

We have discussed crosstalk between organs, such as the gut and heart (Jahng et al., 2016), or the nervous system and various organs (Battaglini et al., 2024)

Crosstalk also takes place between polyphenols and organs, for example, the gut microbiota (Zeb et al., 2024). According to Zeb's group, it takes communications between polyphenols and the community of organisms in the gut (gut microbiota) to prevent cancer.

A synergetic relationship is formed between the molecules of polyphenols and the organisms of the gut to work toward health, performing many functions such as modulating signaling pathways and immune repose, as well as initiating epigenetic modifications (Zeb et al., 2024)

 Koudoufio et al. (2020) describe the crosstalk as an interaction between polyphenols and the micro-ecology promotes multiple physiologcal functions. Gut ecology is the interaction of all the organisms, the relationship to each other and their environment which is the gut. Polyphenols interact with this community - and actually shift the environment at large, initiating a host of activities that influence not only the gut but the body as a whole.

These two articles are excellent education tools.

Enjoy.  

No 7 Systemic Booster

Yours as always,

Dohrea 

References

  • Battaglini, D., De Rosa, S., & Godoy, D. A. (2024). Crosstalk between the nervous system and systemic organs in acute brain injury. Neurocritical Care40(1), 337-348.
  • BAYRAKTAR, M. K., & ACAR, M. N. (2023). The Health Effects of Polyphenols and Mental Health. BIDGE Publications
  • Jahng, J. W. S., Song, E., & Sweeney, G. (2016). Crosstalk between the heart and peripheral organs in heart failure. Experimental & molecular medicine48(3), e217-e217. Article
  • Koudoufio, M., Desjardins, Y., Feldman, F., Spahis, S., Delvin, E., & Levy, E. (2020). Insight into polyphenol and gut microbiota crosstalk: are their metabolites the key to understand protective effects against metabolic disorders?. Antioxidants9(10), 982. Article
  • Labanya, R., & Singh, A. THE NUTRITIONAL POWERHOUSES HIDDEN IN BERRIES AND EMERGING TRENDS FOR REVOLUTIONIZING MEDICINE: A REVIEW.
  • Malik, A., Raghav, N., & Mor, N. (2024). Garlic (Allium sativum L.): A mini review on its multiple pharmacological benefits for human health. Chemistry & Biology Interface14(3). Abstract
  • Zeb, F., Naqeeb, H., Osaili, T., Faris, M. E., Ismail, L. C., Obaid, R. S., ... & Alam, I. (2024). Molecular crosstalk between polyphenols and gut microbiota in cancer prevention. Nutrition Research124, 21-42. Article

      We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.  

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      Tune in to this short film! It brought tears to my eyes as I saw such beautiful people doing so much work with such passion and joy - spreading a message of peace. 

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