Sulforaphane in 2024 Research: What Does It Not Do?
I went deeply into the research on Broccoli Sprouts and Sulforaphane - and realized that just in the last year, so much more information and findings have surfaced.
Take a look at some of these discoveries:
Broccoli Sprouts are rich in glucosinolates and sulforaphane - and the health benefits are growing each year (Li et al., 2024). A quick glance in 2024 research shows powerful anti-microbial activity against pathogens (He et al., 2024), rebuilding the gut microbiome (Bouranis et al., 2024), anti-Alzheimer's activity (Uthaman et al., 2025), Osteoarthritis (davidson et al., 2024), and digestion (Zhu et al., 2024).
And we haven't even touched upon broccoli sprouts amazing work with the liver (Cascajosa-Lira et al., 2024)!
An article on mitochondrial myopathies caught my eyes as this means that sulforaphane helps neuromuscular disorders that are caused by damaged mitochondria and as we know, that is the energy producing organelle in every cell (Lilley et al., 2024).
How is that possible? So many conditions that one food molecule is handling throughout the body. Take a look at the references and choose an article that catches your eye!
Glucosinolates & Sulforaphanes
Enjoy!
References:
- Li, L., Ma, P., Nirasawa, S., & Liu, H. (2024). Formation, immunomodulatory activities, and enhancement of glucosinolates and sulforaphane in broccoli sprouts: a review for maximizing the health benefits to human. Critical Reviews in Food Science and Nutrition, 64(20), 7118-7148. Abstract
- He, L., Jiang, H., Li, Y., Zhang, X., Sun, W., Liu, C., ... & Wang, C. (2024). Sulforaphane-Enriched Extracts from Broccoli Exhibit Antimicrobial Activity against Plant Pathogens, Promising a Natural Antimicrobial Agent for Crop Protection. Biomolecules, 14(3), 352. Article
- Bouranis, J. A., Beaver, L. M., Wong, C. P., Choi, J., Hamer, S., Davis, E. W., ... & Ho, E. (2024). Sulforaphane and Sulforaphane‐Nitrile Metabolism in Humans Following Broccoli Sprout Consumption: Inter‐individual Variation, Association with Gut Microbiome Composition, and Differential Bioactivity. Molecular nutrition & food research, 68(4), 2300286. Abstract
- Lilley, T., Camera, D. M., & Kwa, F. A. (2024). Repairing muscle with broccoli-derived sulforaphane: A preclinical evaluation for the treatment of mitochondrial myopathies. Drug Discovery Today, 104283. Article
- Uthaman, S. K., Kang, W. S., Park, J. Y., Kim, S., Le, D. D., Oh, S. J., ... & Park, J. W. (2025). Endogenous extraction yielded high quality sulforaphane from broccoli sprouts unveils potent antioxidant and anti-Alzheimer's activities. Heliyon. Article
- Davidson, R. K., Watts, L., Beasy, G., Saha, S., Kroon, P., Cassidy, A., ... & Macgregor, A. (2024). The BRoccoli In Osteoarthritis (BRIO study)-A randomised controlled feasibility trial to examine the potential protective effect of broccoli bioactives,(specifically sulforaphane), on osteoarthritis. medRxiv, 2024-06. Article
- Zhu, W., Cremonini, E., Mastaloudis, A. F., Mitchell, A. E., Bornhorst, G. M., & Oteiza, P. I. (2025). Optimization of sulforaphane bioavailability from a glucoraphanin-rich broccoli seed extract in a model of dynamic gastric digestion and absorption by Caco-2 cell monolayers. Food & Function, 16(1), 314-328. Article
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Yours as always
Dohrea
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