Supernatant Synbiotic Formula

This formula was developed to address the mounting problem of life-threatening hospital-generated infections. Supplying 5 powerful Bulgarian lactic acid bacteria and our famous supernatant, this formula have proven to be a great every day probiotic for general use. It is an exceptional product.

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15.75 billion cfu/cap of certified strains of Traditional Bulgarian pedigreed probiotic with Therapeutic Foods in a synbiotic formula containing B. longum, L. casei, L. acidophilus, L. bulgaricus and S. thermophilus along with Supernatant (the metabolites produced by these 5 probiotics including their ORNs) plus inulin (derived from chicory root fiber).

Advanced freeze-drying technology. 60 caps/bottle. 500 mg/cap. No excipients.

  • Microbiome Technology makes possible the production of hardy and viable pedigreed strains of pure cultures of Traditional Bulgarian probiotics, which are standardized referenced material with molecular identity confirmed routinely by DNA sequencing.
  • Supernatant Synbiotic Formula was developed to address the mounting problem of life threatening hospital generated infections (nosocomal infections) from organisms such as C. difficele, Staph aureus, Klebseilla, and vancomycin-resistant Enterococcus faecium.
  • Supernatant Synbiotic Formula is a combination of:
    • Traditional Bulgarian probiotic strains of B. longum, L. acidophilus, L. casei, L. bulgaricusS. thermophilus. 15.75 billion colony forming units (cfu) per 500mg vegetarian capsule.
    • Supernatant is a combination of the metabolites of these five probiotic bacteria such as their lactic acid, enzymes, vitamins, bacterocins, bio-surfactants, bile salt hydrolase and their ORNS (oligoribonucleotides) which is freeze-dried along with the good bacteria.
    • Inulin derived from organic chicory root, functioning as a prebiotic, and a carrier for the probiotics.
  • The Traditional Bulgarian strains of L. acidophilus, L. casei, and B. longum were chosen to suppress C. diff in the large intestines of humans suffering from ulcerative colitis. The strains were found to be the best amongst 50 others that were tested to manage C. diff infection.
  • The Supernatant Synbiotic Traditional Bulgarian strains:
    • Colonize the GI tract, thereby protecting the membrane from colonization by pathogenic bacteria including C. difficile.
    • Promote the production of short-chain fatty acids as a byproduct of the fermentation of inulin by Bifidobacterium. This reduces the intestinal pH and creates an unfavorable environment for C. difficile. Short chain fatty acids are also known to be the main nutritive energy source for the enterocytes. Increased production of short chain fatty acids improves the overall integrity of the GI tract membrane, tightening up cell junctions.
    • Release antibacterial substances such as bacteriocines, which suppress the growth of pathogenic bacteria.
    • Produce metabolic substances such as vitamins, folic acid, folates, amino acids and enzymes.
    • Provide immunogenicity that helps regulate the immune responses during CDAD.
  • Activates a highly preferable, non-specific healthy immune response.
  • Catalyzes a rapid healthy activation of cell-mediated immune response components (Th1 and Th2) and blood serum antibodies (B cells).
  • Stimulate healthy production of mucins for the protection of the GI tracts lining cells.
  • Increase the absorption of liquids (decreasing symptoms of diarrhea) and minerals including sodium, which is responsible for watery stools.
  • Lower blood pressure through ACE inhibition by the metabolite and L. helveticus.
  • Supernatant contains metabolic byproducts of these five lactic acid bacteria such as their lactic acid, amino acids, folates, bacteriocines, bio-surfactants, enzymes (BSH-bile salts hydrolase, lactase) and immune-stimulating substances such as their ORNs (microRNAs). Recent research has shown that ORNs for priming the immune system.
  • Promote maintenance of healthy blood pressure through inhibition of Angiotensin Converting Enzyme (ACE).
  • The primary function of Angiotensin Converting Enzyme (ACE) is to help regulate arterial pressure by converting angiotensin I to angiotensin II.
  • Angiotensin I by itself is inactive, but when converted by ACE to the active form, angiotensin II, it causes narrowing of the small blood vessels in tissues, resulting in an increase in blood pressure (hypertension).
  • High activity or concentration of ACE in the bloodstream generates more angiotensin II, which makes it a marker for cardiovascular and respiratory disease.
  • Angiotensin II also stimulates aldosterone, a hormone that causes hypertension.
  • Supernatant inhibits ACE activity.
  • Induce a highly preferable, non-specific, healthy immune response.
  • Promotes rapid healthy activation of cell-mediated immune response components (Th1 and Th2) and blood serum antibodies (B cells). The formation of the blood serum antibodies is the main advantage of these substances.
  • The multi-directional and synergistic activity of lactic acids, amino acids, folates (Vitamin B), bacteriocines, bio-surfactants and enzymes is indispensable for the healthy function of the human gastrointestinal tract.
  • No filler, flowing agents or excipients of any kind.




BioImmersion Probiotic Master Blend – ProbioticsBifidobacterium longum, Lactobacillus casei, Lactobacillus acidophilus, Lactobacillus bulgaricus and streptococcus thermophilusPrebiotic- Inulin from chicory Root; Supernatant- probiotic metabolites, and ORNs. 15 billion CFU.

Capsule- Cellulose & Water

Suggested Use

Suggested Use

SUPERNATANT— The supernatant is designed to address hospital generated infections.*

Hospital generated infections: Take 2-4 during a hospital stay, or if infected with organisms such as C. difficile (causing diarrhea). It is used to address salmonella, food poisoning, yeast overgrowth, etc. It is also supportive with colitis, diverticulitis, and Crohn’s disease.*

Colds and flu: Take 1-2 capsules a day. Add 1 teaspoon of Lact ORNs and dissolve in mouth. Add 1-2 capsules of Garlic.*

ASD (autistic spectrum disorder): many health care providers find the Supernatant is well tolerated by children with ASD. If 1 capsule is too much, open up the capsule and mix half the amount of the powder with water.*

An everyday probiotic: Due to its strong protection and ability colonize and compete against pathogens, the Supernatant is an excellent choice for everyday probiotic. Take 1-2 daily as maintenance.*

Our Favorite: The Supernatant is such an advanced probiotic product. Our CEO, Seann Bardell, considers it his most favorite product, alongside the Garlic, Phyto Power,and Fructo Borate.

As a probiotic mix it helps even the most sensitive people!*