Cranberries and prostate cancer
Dear Friends
Prostate cancer is one of the most common cancers in the Western world. It is also one of the leading causes of cancer death among men in the United States (CDC).
MMP-2 secretion is elevated in several types of human cancers and their elevated expression has been associated with poor prognosis (Neto, 2007).
Have Cranberries shown in research to offer any help?
We have seen in previous research studies that cranberries contain elements that are shown to be cancer fighting, such as ellagic acid. Joseph (2002) also reported that cranberries contain another element that is shown to help in the fight against cancer, “one of the most potent cancer fighters—EGCG” (p. 50).
Deziel et al. sheds some positive light on cranberry’s anti-cancer potential: Proanthocyanidins from the American Cranberry (vaccinium macrocarpon) inhibit matrix metalloproteinase-2 and matrix metalloprotein-9 activity in human prostate cancer cells via alterations in multiple cellular signaling pathways. Journal of Cellular Biochemistry; 111(3):742-754 Oct 2010
For doctors and scientists: Their research suggested that in fact cranberry proanthocyanidins decreases MMP activity through the induction and/or inhibition of specific temporal MMP regulators, such as increasing the expression of TIMP-2, a known inhibitor of MMP activity; and by affecting the expression of MAP kinase, PI-3 kinase, NF-KappaB, and AP-1 pathway proteins.
For the rest of us: This means the process that cranberries initiate in the body has a great potential to prevent the development of cancerous cells.
The research team agreed that cranberry shows itself to be a strong candidate for further research as a novel anti-cancer agents.
References
Joseph, J.A., Nadeau, D.A., & Underwood, A. (2002). The color code: A revolutionary eating plan for optimum health. New York, NY: Hyperion.
Neto, C. C. (2007). Cranberry and its phytochemicals: a review of in vitro anticancer studies. The Journal of nutrition, 137(1), 186S-193S.
Sincerely yours,
Seann Bardell
Clinical Notes:
The Cranberry Pomegranate Synbiotic Formula contains: organic, freeze-dried cranberry extract, organic freeze-dried pomegranate extract, Lactobacillus casei, Lactobacillus acidophilus, Bifido longum, supernatant (inactive cells of L. bulgaricus and S. thermophilus plus their metabolites), D-Mannose and Inulin.
Click on the link if you want more information
The suggested dosage as a general probiotic supplement is 1 to 2 capsules daily.
The Last Quiz Answer:
The three amigos. A band of brothers making their way through the thicket on the Serregetti plains of Africa—going for a hunt. Female cheetahs typically have a litter of three cubs and live with them for around two years. Male cheetahs live alone or in small groups, these three are littermates. Perhaps only 7,000 to 10,000 of these big cats remain, as the grasslands they favor are disappearing to human settlers.
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