Gut-Brain connection and Autism
Dear Friends,
Over the years research has shown a powerful connection between the gut and brain, some call the GI tract the second brain.
Anywhere from 40 to 90 percent of children with autism suffer from gastrointestinal symptoms (Schmidt C. 2015).
An over use of antibiotics can lead to overgrowth of the Clostridial genus, and overgrowth of Clostridia is indicated in autism and even schizophrenia (Shaw, 2010).
A compound identified as 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPH), which is produced by multiple species of anaerobic bacteria of the Clostridium genus, creates gut inflammation and depletes brain catecholamines.
Add to the above an overuse of other medications such as cortico-steroids, bad dietary patterns and too much stress, and the results you get are a weaken gastrointestinal immune system, and a leaky gut—a viscious cycle of chronic inflammation.
- Schmidt C. 2015. Mental Health: Thinking from the Gut. Nature; 518:512-515
- Shaw W. 2010. Increased urinary excretion of a 3-(3-hydroxphyenyl)-3-hydroxypropionic acid (HPHPH), an abnormal phenylalanine metabolite of Clostridia spp. in the gastrointestinal tract, in urine samples from patients with autism and schizophrenia. Nutritional Neuroscience; 12(3):135-143
How can the Supernatant Synbiotic and the LactORN help?
We developed the Supernatant Synbiotic formula to protect against hospital and healthcare generated infections, of which Clostridium difficile is one of the leading culprits. C. diff. caused almost half a million infections among patients in the United States in a single year, according to a study released by the CDC (CDC Newsroom Feb. 2015). And, Clostridial overgrowth is commonly associated with Autism Spectrum Disorder (ASD).
Our Bulgarian scientists selected strains of lactic acid bacteria that have the best hit against C. difficile— those that produced the strongest bacterocins to inhibit the overgrowth of Clostridia. We have had wonderful feedback from doctors using the Supernatant Synbiotic with patients suffering from recurrent ulcerative colitis and from those treating autistic patients.
LactORN, our newest synbiotic, highlights the power of supplying optimal amounts of the bacterial microRNA, which stimulates the innate immune system compromised by stress to be more able to defend the gut against infectious bacteria and virus. It also recenters the adaptive immune system so that it doesn’t overreact to incompletely digested peptides, xenobiotics, and bacterial endotoxins such as LPS.
So there you have it. See the dosing pattern in the clinical notes.
Sincerely yours,
Seann Bardell
BioImmersion.com
Clinical Note:
The suggested dosing is as follow:
Supernatant Synbiotic one capsule a day or as directed by your doctor.
The LactORN Synbiotic- two level teaspoons a week dissolved in the mouth or as directed by your doctor.
Green Facts
The Marion Institute is very special. It is a root cause solution based non-profit that acts as an incubator for programs and seridipity projects.
Round the Bend Farm- a Center for Restorative Community is one of their important projects, and Desa Van Laarhoven is its director. Hear her keynote speach—Desa’s story.