Activating Short Chain Fatty Acids and Immune Function with Polyphenols
Short chain fatty acids (SCFA) such as acetate, propionate, and butyrate are metabolites formed in the colon by probiotic bacteria munching on indigestible carbohydrates.
SCFA provide energy source ,modulate the immune system, and function as metabolic regulators. One of the most important factors the induce higher levels of SCFA is the presence of polyphenols (Ekbatan et al., 2016).
Polyphenols from apples or pomegranate combined with probiotics activate and enchance the production of SCFA - via activation of their metabolic function. And when incubated together for 3 hours, the supernatant of the probiotics (metabolites) showed an increase of anti-inflammatory activity (Kawabata et al., 2013).
The relationships between probiotics and polyphenols is synergistic - probiotics thrive on polyphenols, and polyphenols get digested and broken-down, perfect for the body's utilization of these molecules.
I have chosen to feature two products that have potent polyphenols and a probiotic with Supernatant, with organisms that have been researched to be effective for digestion, immune building, and as these research articles point out - activating Short chain fatty acids for stronger gut walls, immune boosting, anti-inflammatory, and energy.
Enjoy!
Yours as Always,
Dohrea
References:
- Ekbatan, S. S., Sleno, L., Sabally, K., Khairallah, J., Azadi, B., Rodes, L., ... & Kubow, S. (2016). Biotransformation of polyphenols in a dynamic multistage gastrointestinal model. Food chemistry, 204, 453-462.
- Kawabata, K., Yoshioka, Y., & Terao, J. (2019). Role of intestinal microbiota in the bioavailability and physiological functions of dietary polyphenols. Molecules, 24(2), 370. Article
- Kawabata, K., Sugiyama, Y., Sakano, T., & Ohigashi, H. (2013). Flavonols enhanced production of anti‐inflammatory substance (s) by Bifidobacterium adolescentis: Prebiotic actions of galangin, quercetin, and fisetin. Biofactors, 39(4), 422-429.
- Kawabata, K., Baba, N., Sakano, T., Hamano, Y., Taira, S., Tamura, A., ... & Ohigashi, H. (2018). Functional properties of anti-inflammatory substances from quercetin-treated Bifidobacterium adolescentis. Bioscience, Biotechnology, and Biochemistry, 82(4), 689-697.
Yours as always,
Dohrea
We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.
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