Probiotics & Polyphenols in health
Dear Friends
No. 7 brings together the power of the polyphenols with pedigreeds strains of probiotics.
A reduced life span is an outcome associated with many prevalent diseases, including diabetes, obesity, and high blood pressure. In seeking to prevent these diseases, many researchers have looked into potential therapeutic benefits of naturally occurring compounds.
AMP-activated protein kinase (AMPK) is a major metabolic-sensing protein implicated in the prevention of metabolic disorders, or in minimizing the effects thereof, via the regulation of both upstream and downstream target molecules.
In the field of food and nutrition, the current focus lies in the finding of components that activate AMPK. AMPK is a serine/threonine protein kinase and is activated by several natural compounds, including resveratrol, epigallocatechin gallate, berberine, and quercetin. AMPK activation can induce ATP (adenosine triphosphate) generation through pathways such as glycolysis and β-oxidation. By contrast, ATP-consuming pathways, including fatty acid and cholesterol syntheses, and gluconeogenesis, are suppressed by AMPK activation.
The No. 7 Systemic Booster suggestion daily dose: 1 tsp.
Food Science
We used to think of the colon as a storage place for fecal matter, on its way out, whose function was to reabsorb water and minerals. Now, thru the worldwide research on the human microbiome, we understand that the colon is home to another digestive organ in our body- the GI Microbiome, whose metabolic capacity is 100 fold that of our liver.
A healthy gut microbiome residing in the colon is “the organ” in our body that consumes the fibers (inulins, pectins, beta glucans, resistant starches) and polyphenols in our diet as food, breaking down the longer phenolic chains into shorter ones that are more bioavailable, enabling these phytochemicals to enter into our body and hometically supply their multitude of benefits towards the health of all bodily systems.
Therefore, seeding the digestive system with proven probiotic organisms and bringing in a healthy mix of plants, berries and fruits into your diet is an absolute must for health now and for health long in one’s old age.
References
- Duda-Chodak, A., Tarko, T., Satora, P., & Sroka, P. (2015). Interaction of dietary compounds, especially polyphenols, with the intestinal microbiota: a review. European journal of nutrition, 54(3), 325-341. https://link.springer.com/article/10.1007/s00394-015-0852-y
- Hwang, J. T., Kwon, D. Y., & Yoon, S. H. (2009). AMP-activated protein kinase: a potential target for the diseases prevention by natural occurring polyphenols. New biotechnology, 26(1-2), 17-22 https://www.sciencedirect.com/science/article/pii/S1871678409000557
- Possemiers, S., Bolca, S., Verstraete, W., & Heyerick, A. (2011). The intestinal microbiome: a separate organ inside the body with the metabolic potential to influence the bioactivity of botanicals. Fitoterapia, 82(1), 53-66. https://www.sciencedirect.com/science/article/pii/S0367326X10001899?via%3Dihub
Sincerely yours,
Seann
We have developed our products based on scientific research and/or the practical experience of many healthcare practitioners. There is a growing body of literature on food based nutrition and supplements and their application in support of our health. Please use our products under the advisement of your doctor.
Green Facts:
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